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DHEA-S
"As I've gotten older I've lost vitality, mental sharpness, and resilience. I want the hormone that supports all of it."

The vitality hormone your body stopped making.

DHEA (dehydroepiandrosterone) is a steroid hormone your body produces naturally — and stops producing as you age. Its decline is linked to cognitive decline, bone weakness, cardiovascular disease, depression, and reduced immune function. Bio-identical DHEA replacement addresses all of it.

Cognitive decline, poor concentration, or loss of mental sharpness
Bone weakness, reduced density, or elevated osteoporosis risk
Depression, anxiety, or low mood with a hormonal component
Reduced vitality, low immune function, or increased susceptibility to illness
DHEA hormone therapy at IUVENTUS Medical Center Las Vegas
Delivery options
Oral · Injection · Vaginal
matched to your preference and absorption
Bio-identical DHEA
Physician-supervised · Las Vegas
What it treats

DHEA decline causes seven distinct problems. Replacement addresses all seven.

As the body stops producing DHEA at older age, the consequences are systemic — affecting cognition, bone, cardiovascular health, mood, immunity, skin, and cancer risk. Bio-identical DHEA replacement restores the hormone that supports all of these functions.

🧠
Cognitive Decline & Brain Function

DHEA decline is directly linked to cognitive decline — reduced concentration, memory, and mental sharpness. DHEA supports neurological function through its conversion to estrogen and testosterone in the brain, and through direct neuroprotective effects. Replacement therapy produces measurable improvements in cognitive efficiency in patients with age-related decline.

🦴
Bone Density & Osteoporosis Prevention

DHEA plays a supporting role in bone mineral density — its conversion to sex hormones (estrogen and testosterone) directly influences osteoblast activity and bone formation. Higher DHEA levels are associated with higher bone density. Replacement therapy contributes to bone protection, particularly in post-menopausal women where multiple hormonal deficiencies combine to accelerate bone loss.

❤️
Cardiovascular Disease Risk Reduction

Low DHEA levels are associated with increased cardiovascular disease risk. DHEA has direct anti-inflammatory effects on vascular endothelium and influences lipid metabolism in ways that reduce cardiac event risk. Replacement therapy reduces the risk of life-threatening cardiac events — particularly relevant for aging patients with multiple cardiovascular risk factors.

😌
Depression & Anxiety Relief

DHEA influences serotonin and dopamine pathways — its decline is associated with depression and anxiety, particularly in older adults. The hormone has direct antidepressant properties in addition to its indirect effects through conversion to sex hormones. Replacement produces relief from anxiety and depression that has a hormonal rather than psychiatric root.

🛡️
Immune Function Enhancement

DHEA is an important modulator of immune function — it supports T-cell activity and natural killer cell function, and has anti-inflammatory effects that reduce the chronic low-grade inflammation associated with aging (inflammaging). Replacement enhances higher immune function in patients whose immune resilience has declined with age.

🌸
Women's Health — Vaginal & Sexual Function

For women, DHEA therapy reduces pain during sex by supporting vaginal tissue health — DHEA is locally converted to estrogen and testosterone in vaginal tissue, restoring the moisture and elasticity that decline with hormonal aging. Available in vaginal delivery format for targeted local effect alongside or instead of systemic treatment.

DHEA decline is a natural part of aging. Replacement therapy is a natural way to address it.

DHEA can be taken orally, by injection, or vaginally — your medical team helps determine which delivery method is best for your situation and goals. The right approach depends on your lab results, symptoms, and the rest of your hormonal protocol.

DHEA hormone replacement therapy at IUVENTUS Medical Center
What is DHEA?

The hormone precursor that feeds your entire system.

DHEA (dehydroepiandrosterone) is a steroid hormone produced naturally by the adrenal glands — the most abundant steroid hormone in the human body during young adulthood. It serves as a precursor to both estrogen and testosterone, meaning virtually every sex hormone in the body depends on adequate DHEA levels as a starting material. DHEA production peaks in the mid-20s and declines steadily from there — by age 70, most people have only 10–20% of their peak DHEA levels.

This decline has systemic consequences because DHEA's effects extend beyond its role as a hormone precursor. DHEA has direct neuroprotective effects in the brain, direct anti-inflammatory effects in the cardiovascular system, direct immune-modulatory effects on T-cells, and direct effects on bone mineral density. Its replacement — using bio-identical DHEA that is molecularly identical to what the adrenal glands produce — addresses all of these systems simultaneously.

Bio-identical DHEA replacement at Iuventus is individualized to your lab results. DHEA-S (the sulfated storage form measured in blood) is tested before prescribing — dose is calibrated to restore levels appropriate for your age and symptom profile, not to a standard protocol. Available in oral capsule, injection, or vaginal delivery depending on your goals and absorption needs.

10–20%
of peak DHEA level remaining by age 70 — a dramatic systemic decline
Precursor
to both estrogen and testosterone — DHEA feeds the entire sex hormone system
8 benefits
documented in the site: cognition, bone, heart, mood, immunity, skin, libido, cancer risk
🔬
The 8 benefits of DHEA replacement therapy

Relief from anxiety and depression · Increased cognitive efficiency · Reduced pain during sex for women · Higher bone density · Reduced risk of life-threatening cardiac events · Better insulin regulation · Higher immune function · Better skin appearance · Reduced risks for cancer. Available as oral capsule, injection, or vaginal preparation — your physician determines the best delivery method for your situation.

The research is clear

DHEA is the most abundant steroid hormone in the human body.

Its decline with age affects virtually every system — cognition, bone, cardiovascular, immune, and reproductive. Bio-identical replacement restores the precursor that all sex hormones depend on.

10–20%
of peak DHEA level remaining by age 70 — most people are severely depleted without knowing it
Endocrine literature
8
Documented health benefits of DHEA replacement — from cognition to cardiovascular to immune function
Iuventus Medical Center / Clinical research
3 formats
Oral, injection, or vaginal — matched to your symptoms, goals, and absorption preference
Iuventus Medical Center
How It Works

From depleted to restored vitality.

01
🗓️
Consultation

We discuss your symptoms, health history, and goals. DHEA is almost always assessed alongside other hormones — estrogen, testosterone, cortisol, and thyroid — because they interact. We never prescribe DHEA in isolation without the full hormonal picture.

02
🔬
Lab Testing — DHEA-S

Serum DHEA-S measured alongside your full hormonal panel. Results within 24–48 hours. Your DHEA-S level determines the appropriate starting dose — we don't use standard doses regardless of where your level actually is.

03
📋
Protocol Design

Delivery format — oral, injection, or vaginal — selected based on your goals and absorption profile. Oral is most common for systemic effects. Vaginal for targeted local women's health benefit. Dose individualized to your DHEA-S level and symptom response.

04
📈
Monitoring & Optimization

Follow-up DHEA-S at 6–8 weeks to confirm therapeutic levels. Dose adjusted as needed. Quarterly monitoring ongoing — DHEA interacts with other hormones and the full panel is reassessed at every follow-up.

Why Choose Us

Medicine that
gets you.

DHEA is a hormone with widespread systemic effects — it should always be prescribed in the context of a full hormonal assessment, not as a standalone supplement.

01

Always in Context of Full Panel

DHEA interacts with estrogen, testosterone, cortisol, and thyroid. We never prescribe DHEA in isolation — we assess the full hormonal picture and design DHEA replacement as part of an integrated protocol.

02

Three Delivery Formats

Oral for systemic effects — the most common approach. Injection for patients with absorption issues or specific dosing needs. Vaginal for women seeking targeted local effects on vaginal tissue and sexual comfort. We match the format to your situation.

03

Dosed to Your Labs, Not a Standard Protocol

DHEA-S is measured before prescribing and the dose is calibrated to your specific level and symptoms. Over-supplementation of DHEA can produce unwanted androgenic effects — which is why physician-supervised dosing matters.

04

Experienced Team

Our medical team has been helping people in the Las Vegas area for years with bio-identical hormone therapy — DHEA included. When you come to your appointment, you will be informed of every conclusion regarding your hormonal health, and a treatment plan will be developed suited to your lifestyle and goals.

Patient Stories

Vitality restored
through the right hormone.

★★★★★

"I came in for a general hormone panel and found my DHEA-S was at the level of a 75-year-old at age 55. I hadn't connected the cognitive fog and low resilience I'd been experiencing to DHEA specifically. Six months into replacement therapy my mental clarity and physical energy are noticeably different."

WB
William B.
DHEA-S Replacement · 55 yrs · Las Vegas
★★★★★

"I was on estrogen and progesterone for two years and still felt like something was missing — particularly the energy and mental sharpness. My physician checked my DHEA-S — it was extremely low. Adding DHEA to my protocol was the piece that completed the picture. The cognitive improvement was the most significant change."

JP
Janet P.
BHRT — Estrogen + Progesterone + DHEA · 59 yrs
★★★★★

"My immune system has been terrible for years — every illness caught me and took twice as long to recover. My DHEA was depleted. After four months of replacement, my resilience is genuinely better. I've been told DHEA is the 'immune hormone' and I understand why now."

LG
Linda G.
DHEA-S — Immune Support · 62 yrs
Common Questions

Everything you
want to know.

Bio-identical DHEA is safe when properly dosed and monitored by a physician. The main risks of unsupervised DHEA supplementation are androgenic side effects in women (acne, hair growth, voice changes) from excessive conversion to testosterone — which is why physician-supervised dosing calibrated to your DHEA-S lab level is important. At appropriate therapeutic doses matched to your deficiency, DHEA has a well-established safety profile.
DHEA is available as an over-the-counter supplement in the US — but OTC DHEA products are unregulated, variable in actual dose content, and not calibrated to your specific DHEA-S level. Taking a standard OTC dose without knowing your starting level means you may be significantly under-dosing or over-dosing. Bio-identical DHEA prescribed by a physician is dosed to your lab results and monitored over time — a fundamentally different and safer approach.
DHEA is the primary precursor to both estrogen and testosterone — the body converts it to these hormones in peripheral tissues. This means DHEA levels influence your estrogen and testosterone balance. Adding DHEA to an existing BHRT protocol can shift the estrogen-testosterone ratio and may require adjustment of other hormone doses. This is why we always assess DHEA in the context of your full hormonal panel rather than in isolation.
Oral DHEA is the most common format for systemic effects — straightforward to dose and monitor. Injectable DHEA provides more controlled pharmacokinetics and is preferred for patients with absorption issues. Vaginal DHEA (as Intrarosa, the FDA-approved vaginal DHEA preparation) is specifically designed for women seeking local vaginal tissue benefits — restoring estrogen and testosterone in vaginal tissue locally without significant systemic absorption. Your physician recommends the right format based on your goals and overall protocol.
Most patients notice initial improvements in mood and energy within 4–6 weeks. Cognitive effects typically develop over 2–3 months as neurological function responds to improved hormone precursor availability. Bone density improvement requires sustained therapy over 12+ months before measurable changes appear on DEXA scan. We set realistic timelines for each benefit at your consultation.
Start Today

Your vitality hormone
is measurable. And replaceable.

A DHEA-S blood test, a full hormonal panel, and a bio-identical replacement protocol dosed to your specific levels. Free consultation at Iuventus Medical Center Las Vegas.